- Oral presentation
- Open Access
Fused 3-dimensional whole-heart coronary artery, coronary vein and myocardial scar imaging at 3 T: Feasibility in patients with ischemic and non-ischemic cardiomyopathy
© White et al; licensee BioMed Central Ltd. 2010
- Published: 21 January 2010
- Coronary Artery
- Cardiac Resynchronization Therapy
- Left Main Coronary Artery
- Myocardial Scar
- Coronary Artery Segment
Patients with cardiomyopathy are frequently considered for vascular-based interventions aimed at improving systolic performance. Cardiac Resynchronization Therapy (CRT) and Coronary Artery Revascularization (CAR) are dependent upon the presence of appropriate vascular targets and health of related myocardium for clinical success. A combined evaluation of coronary vascular targets and myocardial scar may benefit the planning of such procedures.
The mean age was 56.6 ± 14.5 years. Combined coronary MRA and 3D scar imaging was successfully performed in 49 (92%) patients. Of 588 proximal-mid coronary artery and coronary vein segments 570 (97%) were scored as clinically evaluable. The mean quality score of the proximal-mid coronary artery segments and coronary vein segments was 3.1 ± 0.9 and 3.2 ± 0.9, respectively. The SNR and CNR scores were 57.3 ± 35.3 and 48.3 ± 31.6 respectively for the left main coronary artery. The respective vales for the right coronary artery was and 47.2 ± 31.4 and 38.2 ± 28.1, respectively for the right coronary artery. The mean quality score for myocardial scar imaging was 2.90 ± 0.98, with an SNR and CNR of 54.2 ± 29.9 and 49.4 ± 29.3 respectively. Image fusion was successful in all patients with quality scores of 2 or greater.
This study demonstrates clinical feasibility of MRI to provide matched isotropic 3-D imaging of coronary anatomy and myocardial scar. This novel fusion technique has the potential to assist in the pre-procedural planning of vascular-based cardiac interventions where myocardial scar is relevant to clinical response.
This article is published under license to BioMed Central Ltd.