- Oral presentation
- Open Access
Effect of improving spatial or temporal resolution with k-t SENSE acceleration in first pass CMR myocardial perfusion imaging
© Maredia et al; licensee BioMed Central Ltd. 2010
- Published: 21 January 2010
- Cardiac Magnetic Resonance
- Myocardial Perfusion Imaging
- Temporal Resolution
- Hybrid Sequence
- Breathing Artefact
First pass cardiac magnetic resonance (CMR) myocardial perfusion imaging (MPI) requires the acquisition of large amounts of image data in a short time. Acceleration techniques like k-t SENSE exploit spatiotemporal correlations to speed up data acquisition. In myocardial perfusion CMR k-t SENSE has been used to improve spatial resolution, temporal resolution or slice coverage with improvements of endocardial dark rim artefacts reported. To date, there has been no direct comparison between these strategies.
To compare the effect of investing the speed-up afforded by k-t SENSE acceleration in spatial or temporal resolution.
Pulse sequence characteristics. (* assuming 340 mm field of view)
Number of slices
Acquired Voxel Dimensions (mm)*
2.66 × 2.66
1.33 × 1.33
2.66 × 2.76
1.77 × 1.82 × 10
Image Acquisition Time Per Slice (ms)
Image analysis was performed on the middle slice. Image quality was scored 0-3 (0-poor, 3-excellent) and breathing artefacts noted by two readers in consensus. Dark rim artefact was assessed by: thickness (using electronic callipers), duration (frame count) and extent (area of artefact measured by contouring and expressed as a percentage of myocardial area). Friedman Test and repeated measures Analysis of Variance Testing (with Bonferroni correction for pairwise comparisons) were used to compare non-parametric and parametric data respectively.
Image quality and dark rim artefact results.
Mean Image Quality Score
Mean Rim Thickness (mm)
Mean Rim Extent (%)
Mean Rim Duration (frames)
Although spatial and temporal resolution both influence the thickness and extent of dark rim artefact, maximising spatial resolution by k-t SENSE acceleration produces the greatest reduction in these parameters. This may lead to fewer false positive results using CMR MPI in a clinical setting. k-t SENSE remains sensitive to respiratory artefacts.
This article is published under license to BioMed Central Ltd.