- Oral presentation
- Open Access
Visualization of carotid plaque calcification - a novel approach using susceptibility weighted MR imaging
© Yang et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Black-blood sequence has been the method of choice in carotid artery plaque imaging. Susceptibility weighted imaging (SWI) can be used to image the vessel wall and calcifications without the need to suppress the signal from the blood.
To demonstrate the feasibility of susceptibility weighted imaging (SWI) for visualization of carotid artery wall calcifications by MRI using CT as the reference standard.
Methods and materials
A total of 13 calcifications in 6 subjects located in the carotid artery wall were identified with CT. Sensitivity and specificity with SWI was 84.6%(11/13) and 92.8%(13/14), respectively. The mean area of calcification measured on CT and SWI phase images was 0.45 ± 0.13 cm2 and 0.38 ± 0.18 cm2 respectively. The Pearson correlation coefficient of the measured calcification area between CT and SWI phase image is 0.88 (p < 0.001).
Despite the preliminary character, this study clearly indicates that carotid artery wall calcification seen in SWI phase images correlate well in both location and size with the CT results. MRI can therefore offer an alternative approach to CT for detection of plaque calcification.
This article is published under license to BioMed Central Ltd.