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- Open Access
Visceral fat is associated with an adverse increase in the thickness of the wall of the ascending thoracic aorta
© Chughtai et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
An abnormal increase in ascending aortic wall thickness (AOWT) identifies individuals at increased risk for adverse cardiovascular outcomes. Disease states causing increased AOWT invoke changes that are also present in individuals with larger amounts of intraperitoneal (IP) fat.
IP fat is associated with an increase in ascending AOWT, after accounting for other risk factors that promote aortic wall thickness.
240 participants (mean age 69 + 9 years, 50% female) with risk factors for cardiovascular disease underwent magnetic resonance imaging measures of AOWT and abdominal fat (subcutaneous [SC] + IP + retroperitoneal [RP]). Linear regression was used to identify associations between AOWT and subtypes of fat after accounting for confounding factors.
IP fat is independently associated with an abnormal increase in ascending AOWT, a condition associated with adverse cardiovascular events.
This article is published under license to BioMed Central Ltd.