Skip to main content
  • Poster presentation
  • Open access
  • Published:

Time course of myocardial oedema in acute coronary syndrome assessed at 3 T using a bright blood T2-prepared SSFP sequence


Cardiac magnetic resonance (CMR) is used in the evaluation of acute coronary syndrome (ACS) to assess both area at risk (AaR) and area of necrosis. However, the time course and evolution of myocardial oedema in patients with ACS is not known. We sought to assess the change in myocardial oedema following percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) and non-ST elevation ACS (NSTE-ACS).


Patients admitted with NSTE-ACS who underwent PCI within 24 hours, or with STEMI were imaged using CMR (Siemens Trio 3 T) at 24-48 hours (E1) and 5-7 days (E2) post PCI. STEMI patients were also imaged at 14-17 days (E3). The imaging protocol included short axis images covering the entire left ventricle (LV) acquired using T2-prepared SSFP sequence and late gadolinium enhancement (LGE). Percentage of myocardial oedema (oedema area/LV slice area: AaR) and myocardial scar were assessed offline.


We identified two groups of male patients (6 STEMI and 6 NSTE-ACS) matched for age (54 ± 8 yrs vs 59 ± 13 yrs) and AaR at E1 (24 ± 15% and 23 ± 14%).

In NSTEMI patients, AaR decreased to 15.6% (p = 0.10) between E1 and E2. In contrast, in STEMI AaR increased from 24 ± 15% at E1 to 31 ± 15% 5-7 days post PCI (E2). By 14-17 days (E3) there was a significant decrease in oedema (20 ± 13%) in this group.

Myocardial scar assessed by LGE was significantly smaller in NSTE-ACS compared to STEMI (7 ± 9% vs 21 ± 12%;p = 0.05), Figure 1.

figure 1

Figure 1


For equivalent initial area at risk at E1, patients with STEMI have larger scar and more persistent oedema. Myocardial oedema post PCI decreases in NSTE-ACS within 7 days, but increases in STEMI. These dynamic changes highlight the importance of CMR in ACS patients and suggest the need to define the optimal time point to assess area at risk.

Author information

Authors and Affiliations


Rights and permissions

Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and permissions

About this article

Cite this article

Dall'Armellina, E., Lindsay, A.C., Robson, M.D. et al. Time course of myocardial oedema in acute coronary syndrome assessed at 3 T using a bright blood T2-prepared SSFP sequence. J Cardiovasc Magn Reson 12 (Suppl 1), P149 (2010).

Download citation

  • Published:

  • DOI: