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Endocardial extent by contrast enhanced cardiac magnetic resonance imaging is not an accurate method for assessing myocardium at risk; validation with T2-weighted cardiac magnetic resonance imaging
© Ubachs et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
In the situation of acute coronary occlusion, the myocardium supplied by the occluded vessel is subject to ischemia and is referred to as the myocardium at risk (MaR). It has previously been shown that cardiac magnetic resonance (CMR) imaging can be used for the assessment of MaR employing a T2-weighted edema sequence. Recently, it has been suggested that the endocardial extent of hyperenhancement as assessed by contrast enhanced CMR can also be used to quantify the MaR.
We sought to assess the ability of endocardial extent by contrast enhanced CMR to quantify MaR in relation to T2-weighted edema imaging.
Thirty-six patients with early reperfused first-time ST-segment elevation myocardial infarction underwent CMR imaging within 7 days after percutaneous coronary intervention. The MaR was determined by contrast enhanced endocardial extent and compared to the MaR as determined by T2-weighted edema imaging.
This study demonstrated that the endocardial extent as assessed by contrast enhanced CMR is not an accurate method for the assessment of MaR in patients with early reperfusion, using T2-weighted edema imaging as reference method.
This article is published under license to BioMed Central Ltd.