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Consideration of the impact of reperfusion therapy on the quantitative relationship between the Selvester QRS score and infarct size by cardiac magnetic resonance
Journal of Cardiovascular Magnetic Resonance volume 12, Article number: P176 (2010)
Introduction
It has previously been shown that there is a good agreement between the Selvester QRS score and myocardial infarct (MI) size determined by post mortem histopathology in patients with non-reperfused MI. Currently, however, most patients with acute coronary thrombosis receive reperfusion therapy.
Purpose
The aim of this study was, therefore, to test the hypothesis that early reperfusion alters the quantitative relationship between Selvester QRS score and MI size.
Methods
Twenty-seven patients with acute first-time repefused MI were studied. Infarct size was determined by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) and estimated with the 50-criteria/31-point Selvester QRS scoring system one week after admission. The findings in the present study were compared with previous post mortem studies exploring the quantitative relationship between Selvester QRS score and MI size in non-reperfused patients.
Results
The quantitative relationship between QRS score and MI size by LGE-CMR in the present study of early reperfused MI was significantly different (p < 0.0001) from previous post mortem histopathology studies of non-reperfused MI. In the present study, each QRS point represented approximately 2% left ventricle (Figure 1A), compared to approximately 3% in previous post mortem histopathology studies of non-reperfused MI (Figure 1B).

Figure 1
Conclusion
There is a different quantitative relationship between QRS score and MI size in early reperfused MI compared to non-reperfused MI, partly explained by differences in MI size. Thus, the Selvester QRS scoring system may not be linearly related to MI size.
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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Knippenberg, S.A., Wagner, G.S., Hedström, E. et al. Consideration of the impact of reperfusion therapy on the quantitative relationship between the Selvester QRS score and infarct size by cardiac magnetic resonance. J Cardiovasc Magn Reson 12 (Suppl 1), P176 (2010). https://doi.org/10.1186/1532-429X-12-S1-P176
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DOI: https://doi.org/10.1186/1532-429X-12-S1-P176