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Consideration of the impact of reperfusion therapy on the quantitative relationship between the Selvester QRS score and infarct size by cardiac magnetic resonance
© Knippenberg et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
It has previously been shown that there is a good agreement between the Selvester QRS score and myocardial infarct (MI) size determined by post mortem histopathology in patients with non-reperfused MI. Currently, however, most patients with acute coronary thrombosis receive reperfusion therapy.
The aim of this study was, therefore, to test the hypothesis that early reperfusion alters the quantitative relationship between Selvester QRS score and MI size.
Twenty-seven patients with acute first-time repefused MI were studied. Infarct size was determined by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) and estimated with the 50-criteria/31-point Selvester QRS scoring system one week after admission. The findings in the present study were compared with previous post mortem studies exploring the quantitative relationship between Selvester QRS score and MI size in non-reperfused patients.
There is a different quantitative relationship between QRS score and MI size in early reperfused MI compared to non-reperfused MI, partly explained by differences in MI size. Thus, the Selvester QRS scoring system may not be linearly related to MI size.
This article is published under license to BioMed Central Ltd.