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- Open Access
Assesment of cardiac volumes in children with congenital heart disease using a 3D dual cardiac phase technique and a new segmentation tool
© Hussain et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
For children with complex congenital heart disease (CHD), the decision regarding univentricular or biventricular surgical repair may depend on accurate ventricular volume assessment. We have previously shown that three-dimensional (3d) whole-heart imaging acquired during end-systole and end-diastole (dual-phase) during one free-breathing MRI examination, when combined with semi-automatic analysis, may be more reproducible in calculating ventricular volumes than standard techniques (Uribe et al, 2008). We describe here, for the first time, use of 3d dual-phase imaging in children with complex CHD.
To show 3d dual-phase imaging is feasible in children with complex CHD despite high heart rates.
Number of Patients
Repaired Pulmonary Atresia, VSD, Major Aorto-Pulmonary Collaterals with severely dilated RV
Hypoplastic Left Heart Syndrome; Status Post Glenn Procedure
Hypoplastic Left Heart Syndrome; Status Post Norwood Procedure
Left Atrial Isomerism, Univentricular AV connection, Solitary RV, Aortic Atresia, Dextrocardia, Azygous continuation. Status Post Norwood
Transposition of Great Arteries, VSD, Pulmonary Stenosis, Dextrocardia, Status Post Rastelli Procedure
Situs Solitus, AV concordance, VA disconcordance, Dextrocardia, Unbalanced AVSD with Rudimentary Left Ventricle, Status Post Glenn
Situs Solitus, AV concordance, Pulmonary Atresia with Aorta from RV, Unbalanced AVSD with Rudimentary Left Ventricle, Status Post Modified Blalock-Thomas-Taussig shunt
Unrepaired Tetralogy of Fallot, with Major Aorto-Pulmonary Collaterals.
Double Inlet Left Ventricle, Pulmonary Atresia, Status Post Glenn Procedure
Standard ventricular analysis involves manual segmentation of cross-sectional cine images acquired over several breath-holds. This can have problems with slice misalignment. Furthermore, lack of isotropic resolution (by using thick slices which move during the cardiac cycle) makes definition of atrio-ventricular & ventriculo-arterial boundaries difficult. Therefore, acquisition and segmentation relies on operator experience. We believe that 3d dual-phase imaging with semi-automatic analysis overcomes these issues. This study demonstrates that 3d dual-phase imaging can successfully be performed even in very young children with complex CHD. Reliable and valid volumetric analysis was possible using the new semi-automatic segmentation technique.
This article is published under license to BioMed Central Ltd.