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Diagnostic value of cardiac magnetic resonance (cmr) before and after pulmonary transcatheter valve implantation: preliminary results
© Francesco et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
CMR can be used for a comprehensive noninvasive assessment of cardiac performance after pulmonary transcatheter valve implantation. A non-invasive evaluation of the valve is foundamental in young pantients
To evaluate the diagnostic value of CMR before and after pulmonary transcatheter valve (Melody, Medtronic) implantation.
After IRB approval and informed consent, patients with pulmonary valve disease were prospectively scheduled for 1.5-T CMR before and after transcatehter valve implantation. We used a cine true-FISP sequence (TR/TE = 45/1.5 ms, thickness 7 mm) for evaluating the right ventricle (RV) function and a turbo-FLASH phase-velocity mapping sequence (41/3.2 ms, 5 mm, respectively; velocity encoding 250 ms) for pulmonary flow evaluation. Pressure gradient (ΔP) was estimated from peak flow velocity using Bernoulli's equation. McNemar and Wilcoxon tests were used.
CMR evaluation of patients after Melody™ implantation is not impaired by metal artifacts outside the valve. One month after implantation, we observed a complete nulling of regurgitant fraction and a significant decrease of ΔP and of ESVI of RV; the other RV parameters showed a trend in favor of a positive implant effect. No significant change was observed for the left ventricle (with a borderline significance for a slightly reduced ESVI).
This article is published under license to BioMed Central Ltd.