A segmented T2-prepared SSFP sequence for T2-weighted imaging and T2-mapping of the myocardium
© Stainsby et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Recent studies demonstrate that hyperintense regions in T2-weighted images in acute myocardial infarction (AMI) reflect the presence of edema  and area at risk. Single-shot T2-prepared SSFP methods have been presented for T2-weighted imaging in AMI . Here a segmented SSFP approach suitable for multi-slice, multi-echo imaging of the myocardium is presented.
To maximize T2 contrast while minimizing eddy current effects , an even-odd, centric phase encode ordering scheme was implemented.
To preserve the prepared T2 contrast across multiple slices an RF chopping scheme  consisting of two averages with an inversion pulse following the T2-preparation on even averages was implemented. This enables subtraction of contaminant signal that recovers with time constant T1.
To preserve in-slice signal integrity, in-slice signal is catalyzed prior to, and spoiled following, data acquisition to minimize cross-slice contamination.
Finally, fat saturation was integrated into the preparation interval  to reduce contributions of recovering fat signal.
T2 values are estimated using a 2-parameter exponential fit or a 3-parameter fit including baseline offset.
A segmented, T2-prepared, multi-slice, multi-echo imaging sequence is presented that can be applied to edema identification in AMI patients.
This article is published under license to BioMed Central Ltd.