- Poster presentation
- Open Access
Inline non-rigid motion-corrected t2 mapping of myocardium
© Giri et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Myocardial T2 is altered in certain pathologies like acute coronary syndrome (ACS), myocarditis and allograft rejection, which have traditionally been detected using T2-weighted (T2W) techniques. These T2W techniques suffer from several drawbacks , most of which can be addressed by a quantitative T2 mapping approach. Single-shot T2-prepared SSFP (T2prep-SSFP) has been proposed for T2 Mapping ; however, image mis-registration due to failed breath-hold or inconsistent cardiac rhythm degrades the accuracy of pixel-wise curve fitting. We propose a comprehensive T2 mapping technique that includes automatic registration of T2prep images with an inline implementation to enable clinical application.
To design and implement a rapid motion corrected inline T2 mapping technique for myocardium.
Three T2prep times were used (Table 1). The non-selective T2prep pulse combined with a fast SSFP readout makes each T2P acquisition insensitive to motion. To correct for motion between images, a fast variational non-rigid registration algorithm  was employed which aligned all T2prep frames to the center frame. T2 maps were then computed by fitting intensities of corrected images to the mono-exponential decay curve: Signal = M0 * exp(-T2prep/T2). Finally, color-coded T2maps were generated inline; the entire post-processing is unsupervised and typical processing time was less than 1 s.
Number of T2Preps
0 (no prep), 24, 55 ms
~ 150 ms
Total acquisition time
9 RR intervals
2.5 × 2.75 × 8 mm
Parallel acquisition/acceleration/reference lines
We have demonstrated a rapid T2 Mapping technique with integrated unsupervised motion correction and inline colormap generation.
This article is published under license to BioMed Central Ltd.