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Highly efficient respiratory gating in coronary MR employing non-rigid retrospective motion correction
© Schmidt et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Three-dimensional whole heart imaging becomes the method of choice in cardiac applications  as it avoids extensive planning of imaging slices and allows reconstructing arbitrary slice orientations. The drawback is a relatively long scan time on the order of several minutes which requires motion compensation to suppress motion artifacts. Prospective techniques such as respiratory navigator based gating or triggering including slice tracking is often used. Recently, retrospective approaches were successfully implemented by extending the image encoding matrix with motion operators and solving the system iteratively [2–4]. This allows for increased gating windows or even continuous scanning across the entire breathing cycle but necessitates detailed information of the underlying motion vector field at each acquisition.
In this work, a template-based approach for retrospective motion correction was used to correct for respiratory motion artifacts in free-breathing coronary MR scans with gating windows as large as 20 mm.
Whole heart images were acquired in six healthy subjects on a 1.5 T Philips Achieva System (Philips Healthcare, Best, The Netherlands). A volunteer-specific motion model was retrieved from a low-resolution multi-2D pre-scan with a voxel size of 4 × 4 × 4 mm3, where each slice was acquired repeatedly in single-shot mode at different respiratory states. The motion vector fields between these respiratory states were then calculated by image registration . Missing respiratory states were linearly interpolated. The actual 3D scan was a standard navigator-gated 3D-BTFE sequence with an increased gating window of 20 mm and a voxel size of 1.33 × 1.33 × 1.33 mm3. An additional 3D scan with a gating window of 5 mm was acquired as reference.
It has been shown that respiratory motion artifacts can be retrospectively corrected using a non-rigid motion model derived from a short pre-scan. The gating efficiency could be doubled and thus scan times reduced. Further work is warranted to determine the robustness of the method in the presence of strong respiratory drifts as can occur in cardiac patients.
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