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- Open Access
Identification and classification the coronary artery plaque with MRI coronary wall imaging - A Comparative Study Using 64-MDCT
© He et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Several studies indicated(1) that high-resolution black blood coronary arterial wall MRI has the potential to assess coronary artery wall thickness, non-invasively and measure plaque burden. But a systematical evaluation of coronary plaque components and morphology by MRI has not been done so far.
To evaluate the ability of black-blood coronary arterial wall MRI to identify and classify coronary artery plaque, using 64-MDCT as reference standard.
13 patients(mean age 56.2 ± 11.8 years, 9 men) with confirmed coronary artery disease by coronary CTA (64-MDCT) underwent black-blood coronary wall MRI within 10 days. All scans were performed on a 1.5 T scanner (MAGNETOM Sonata, Siemens, Germany). Cross-sectional coronary wall imaging was acquired using a 2D double-inversion-recovery, ECG-triggered, navigator-gated, fat-suppressed, Turbo-Spin-Echo sequence (TSE) sequence  on the lesion coronary artery from the ostium to the middle segment continuously without gap. The vessel cross-sectional area (CSA), luminal CSA, maximal wall thickness, plaque burden, CNR (SI vessel wall - SI perivascular area/SD noise) and SNR (SI vessel wall/SD noise) were measured in each slice which were then compared with the CTA images. CTA were divided into 5-mm segments to compared side by side with MRI.
Coronary wall MRI can identify coronary plaque in proximal segments, and also has the potential to differentiate different types of plaques.