- Poster presentation
- Open Access
Single breath-hold whole heart coronary MRA with isotropic spatial resolution using highly-accelerated parallel imaging with a 32-element coil array
© Xu et al; licensee BioMed Central Ltd. 2010
- Published: 21 January 2010
- Steady State Free Precession
- Coil Sensitivity
- Early Systole
- Anatomic Coverage
- Preparation Pulse
Whole heart coronary MRA (CMRA) is typically performed with navigator gating because of the extensive data acquisition needed to achieve an isotropic spatial resolution on the order of 1-2 mm3 with full anatomic coverage (10-16 cm). Previous studies have shown that whole heart CMRA can be performed with either a single  or double [2, 3] breath-hold (BH) approach using highly-accelerated parallel imaging. The single breath-hold approach  acquires the coil sensitivity data immediately before and after the coronary MRA data within the same cardiac cycle, whereas the double BH approach acquires coil sensitivity data in a separate BH. The single BH approach lengthens the time between the T2 and fat suppression pulses to the image acquisition, and the double BH approach may suffer from misregistration. We propose to acquire the coil sensitivity and coronary MRA data in two separate cardiac phases (early systole and mid diastole, respectively) both within a single BH, in order to circumvent the aforementioned problems.
To develop a robust single BH whole heart CMRA scan with isotropic spatial resolution.
We demonstrate the feasibility of performing single BH whole heart CMRA with isotropic spatial resolution. Compared with the double BH approach, the new single BH approach yielded less "pseudo-noise" artifacts in the GRAPPA reconstruction. This approach has the potential to improve diagnostic accuracy for rapid volumetric CMRA.
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