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Prediction of response to cardiac resynchronization therapy by cine- and velocity encoded cardiac magnetic resonance imaging
© Muellerleile et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Quantification of mechanical dyssynchrony can help to identify responders to cardiac resynchronization therapy (CRT).
The purpose of the present study was to evaluate the ability of cine- and velocity encoded (VENC) magnetic resonance imaging (MRI) to predict response to CRT.
The study included twenty patients with heart failure NYHA class III and reduced ejection fraction (24 (18-28) %), scheduled for CRT device implantation. All patients underwent cine- and VENC-MRI before device implantation. Intra-ventricular dyssynchrony was measured by cine-MRI as the septal-to-lateral mechanical delay (SLMD). The inter-ventricular mechanical delay (IVMD) was assessed by VENC-MRI as the difference between onset of aortic and pulmonary flow. Clinical response to CRT was assessed at 6-month follow-up after device implantation.
Cine- and VENC-MRI have the ability to identify responders to CRT.
This article is published under license to BioMed Central Ltd.