Predictive value of electrocardiographic criteria for regional wall thickness in patients with cardiomyopathy
© Donnino et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Electrocardiographic (ECG) criteria for left ventricular (LV) hypertrophy have been shown to have modest predictive values when compared to LV hypertrophy measured by cardiac magnetic resonance (CMR). Prior studies have excluded patients with cardiomyopathies and have not evaluated regional wall thickness in addition to overall LV mass and wall thickness. Thus it remains unknown how well ECG criteria will predict both regional wall thickness and overall LV mass/wall thickness compared to CMR in this population.
To determine if common criteria for LV hypertrophy on ECG are predictive of regional wall thickness and overall LV mass as determined by CMR in patients with cardiomyopathy.
A total of 41 consecutive patients (34 male) greater than 40 years old who underwent CMR for evaluation of cardiomyopathy (both ischemic and non-ischemic) were evaluated. Recent ECG's (mean of 8 days from CMR) were blindly evaluated and patients with a QRS > 120 were excluded from analysis. LV mass and regional wall thickness (anterior, septal, inferior, lateral) were measured at end-diastole on CMR. ECG voltage was examined by two commonly used determinants of LV hypertrophy: 1) Sokolow (SV1+RV5 or V6) and 2) Cornell (SV3+RaVL) criteria. Pearson r correlations were used to examine the relationship between the CMR and ECG parameters.
ECG voltage and CMR correlations
Global LV measurements
LV mass index
Average LV thickness
Regional wall thickness
Sokolow ECG voltage criteria for LV hypertrophy demonstrates good to high correlations with LV mass and regional LV wall thickness in patients with cardiomyopathy. Cornell criteria performed worse in this population. No significant differences existed between LV regional wall thickness for either criteria.
This article is published under license to BioMed Central Ltd.