Percutaneous pulmonary valve implantation in right ventricular outflow tract dysfunction enhances cardiac response to exercise by improved bi-ventricular stroke volume-a exercise stress real-time magnetic resonance study
© Lurz et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Magnetic resonance imaging (MRI) often guides the management of patients with congenital heart disease involving right ventricular outflow tract (RVOT) dysfunction. However, the impact of RVOT dysfunction and its relief on cardiac response to exercise stress is unknown.
To assess the impact of PPVI on bi-ventricular adaptation to exercise
12 patients, who underwent percutaneous pulmonary valve implantation (PPVI) for significant RVOT obstruction (echo gradient > 50 mmHg), were included. MRI was performed at rest and during supine exercise stress at the same intensity pre- and within 1 month post-PPVI. Bi-ventricular volumes and function were assessed under free breathing and continuation of exercise using a radial k-t SENSE real-time sequence. Pulmonary regurgitation fraction was calculated as follows: RV stroke volume (SV) - LV SV.
PPVI for RVOT dysfunction improves bi-ventricular response to exercise. Utilisation of such real-time MR imaging techniques during exercise stress may refine the assessment of procedural success post RVOT interventions in patients with congenital heart disease.
This article is published under license to BioMed Central Ltd.