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Cardiac Cine MR imaging: Fast high-resolution ventricular coverage using TGRAPPA cine SSFP for assessment of systolic and diastolic LV function at 3 Tesla
© Wintersperger et al; licensee BioMed Central Ltd. 2010
Published: 21 January 2010
Cine SSFP imaging represents the standard of reference in assessment of cardiac function at 1.5 and 3 T but is typically associated with an overall examination time of 6-9 min based on a single-slice approach. Real-time techniques allow for a substantial reduction in acquisition time but may also be accompanied with restrictions in spatial and/or temporal resolution. Modern parallel imaging allow for a substantial speed-up in data sampling without necessarily affecting parameters of spatial/temporal resolution.
To implement and evaluate the accuracy of a multi-slice dual-breath hold cine MR technique with high spatial and temporal resolution for analysis of global systolic and diastolic left ventricular (LV) function at 3 T.
Materials and methods
24 patients referred to cardiac MR underwent cine imaging at 3 T (MAGNETOM Verio) using prospective triggered SSFP (TR 3.1 ms; TE 1.4 ms; FA 60°) and a 32-element cardiac coil for signal reception. Analysis of LV function was performed using a standard non-accelerated single-slice approach (STANDARD) with multiple breath-holds and an accelerated multi-slice technique (TGRAPPA; R = 4) encompassing the ventricles with 5 slices/breath-hold. Parameters of spatial and temporal resolution were kept identical (pixel: 1.9 × 2.5 mm2; temporal resolution: 47 ms). Data of both acquisition techniques were analyzed by two readers using semiautomated algorithms (syngoARGUS) in respect to end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), myocardial mass (MM), peak filling rate (PFR) and peak ejection rate (PER) including the assessment of the interobserver agreement. Time efforts for data acquisition and post-processing were also recorded.
Fast multislice dual-breath hold CINE MR imaging at 3 T using TGRAPPA acceleration enables an accurate and reproducible evaluation of global systolic and diastolic left ventricular function at 3 T while substantially reducing data acquisition time.
This article is published under license to BioMed Central Ltd.