- Oral presentation
- Open Access
A novel, automated method for measuring mitral valve annular velocity from standard cine TrueFISP data - a feasibility study
© Weale et al; licensee BioMed Central Ltd. 2011
Published: 2 February 2011
A novel method for determining a correlate of Tissue Doppler Imaging (TDI) parameters from cine TrueFisp data. Using the velocity of automatically identified and tracked landmarks,time/velocity data and hence s', e' and a' can be derived.
To validate mitral valve annular velocities extracted in an automated fashion using an established algorithm for database guided landmark detection and temporal propagation based on inverse consistent non-rigid registration  in a normal population.
To correlate the derived early diastolic myocardial peak-velocity measurements (e prime or e') against phase contrast methods and to evaluate correlation with age.
In a sub-cohort of 6 subjects breath-hold and free breathing phase contrast data (Venc 25cm/s) was acquired in the short axis orientation at a slice position where the myocardium on the apical side of the valve ring was within the slice throughout the cardiac cycle.
Lateral and septal myocardium at the intersection of the four chamber orientation was then evaluated using standard flow post-processing and e' velocities derived.
Lateral and Septal e prime - effect of temporal resolution
Septal e' cm.s-1
Septal Standard Deviation
Lateral e' cm.s-1
Lateral Standard Deviation
Using e' derived from the lateral landmark with 30 ms temporal resolution , a good correlation with both breath-hold and free breathing phase contrast data (r = 0.80 for both) is seen.
Measured e' demonstrates an inverse correlation with subject age (r = - 0.74)
This novel method of deriving mitral annular velocities is potentially a method for extracting data which may correlate with TDI.
It is simple extension of an existing algorithm which provides measurement of s' eand a' from standard imaging data. Validation against TDI is ongoing.
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