- Oral presentation
- Open Access
Cardiac magnetic resonance myocardial feature tracking correlates with natural radial strain and corresponds to inotropic stimulation
Journal of Cardiovascular Magnetic Resonance volume 14, Article number: O50 (2012)
We have demonstrated that cardiac magnetic resonance (CMR) myocardial feature tracking (FT) and natural radial strain correlate and correspond to inotropic stimulation. CMR-FT has the potential for quantitative wall motion assessment at rest and during dobutamine stress magnetic resonance (DSMR) imaging.
CMR-FT is a recently introduced technique for tissue voxel motion tracking on standard steady-state free precession (SSFP) images to derive radial myocardial mechanics. CMR-FT has the potential to facilitate DSMR analysis however has not yet been compared to external reference standards (with stress) such as SSFP derived natural radial strain.
10 healthy subjects were studied at 1.5 Tesla. LV short-axis radial strain ErrSAX was derived from SSFP cine images using dedicated CMR-FT software (Diogenes MRI prototype, Tomtec, Germany) at rest and during dobutamine stress (10 and 20 μg * kg-1* min-1). Natural radial strain values (loge [End-systolic wall thickness/end-diastolic wall thickness]) were calculated in identical segments as analysed for ErrSAX using commercially available software (Philips View Forum, The Netherlands). 95% confidence intervals (CI) of the difference and p-values were calculated to compare the 2 techniques.
In all volunteers strain parameters could be derived from the SSFP images at rest and stress. ErrSAX values showed significantly increased contraction with DSMR (rest: 19.6±14.6; 10 μg: 31.8±20.9; 20 μg: 42.4±25.5, p<0.05). Natural radial strain values increased with dobutamine (rest: 24±8.9; 10 μg: 36.5±8.9; 20 μg: 44.2±8.5, p<0.05).
CMR-FT correlates with natural radial strain derived from SSFP cine imaging. Both measures correspond to inotropic stimulation. CMR-FT holds promise of easy and fast quantification of wall mechanics and strain.
AS receives grant support from the British Heart Foundation (BHF) (RE/08/003 and FS/10/029/28253) and the Biomedical Research Centre (BRC-CTF 196). SK receives grant support from the American College of Cardiology Foundation, the Edna Ittner Pediatric Foundation, and the Children’s Hospital and Medical Center Foundation.
About this article
Cite this article
Schuster, A., Kutty, S., Padiyath, A. et al. Cardiac magnetic resonance myocardial feature tracking correlates with natural radial strain and corresponds to inotropic stimulation. J Cardiovasc Magn Reson 14, O50 (2012). https://doi.org/10.1186/1532-429X-14-S1-O50
- Cardiac Magnetic Resonance
- Dobutamine Stress
- Feature Tracking
- British Heart Foundation