- Oral presentation
- Open Access
Aortic dimensions on cardiovascular magnetic resonance imaging relate to pregnancy outcomes in women with coarctation of the aorta: a multicenter study
© Juan et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Cardiovascular Magnetic Resonance
- Pregnancy Outcome
- Obstetric Complication
- Cardiovascular Magnetic Resonance Imaging
To examine the association between aortic dimensions on cardiovascular magnetic resonance imaging (CMR) and risk of adverse events related to pregnancy in women with coarctation of the aorta (CoA).
Women with CoA are at increased risk of developing complications during pregnancy. The relationship between CMR measures of the aorta and pregnancy outcome is unknown.
Consecutive women seen in several tertiary care institutions with CMR studies (including contrast enhanced-MR angiography) within 2 years of pregnancy were included. Those with aortic stents were excluded. 28 women with CoA (previously repaired n=24 and unrepaired n=4) who had 30 pregnancies were reviewed. Aortic diameters and cross-sectional areas were systematically measured at various predefined levels from the ascending aorta to the level of the diaphragm. Cardiovascular events (hypertension, sustained arrhythmia, heart failure, stroke, cardiac arrest, and/or need for an urgent cardiac procedure), obstetric complications (eclampsia, pre-term labour, post-partum hemorrhage) and fetal/neonatal events (still birth, prematurity, low birthweight, respiratory distress syndrome, intraventricular hemorrhage, death) were recorded.
Demographic details and clinical events
Mean ± SD
Age at intervention (years) (n=28)
Age at pregnancy (years) (n=30)
Age at time of CMR (years) (n=31)
Number of pregnancies (n=28)
3 or more pregnancies
Type of cardiac lesion (n=28)
CoA with bicuspid aortic valve
CoA with additional complex lesion(s)
Type of Intervention (n=28)
Subclavian flap repair
End to end anastomosis
Clinical events (n=30)
Cardiovascular events related to pregnancy
Sustained arrhythmia requiring medical therapy
Small for gestational age
This is the first study to relate pregnancy outcome with morphologic features of the aortic arch in women with CoA. Smaller arch dimensions appear to be associated with cardiovascular and fetal/neonatal complications related to pregnancy. Detailed assessment of the aorta may help identify those at high risk during pregnancy.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.