- Oral presentation
- Open Access
Cardiac magnetic resonance differentiates subtypes in bicuspid aortic valve and reveals various frequencies of aortic stenosis among subtypes
© Wassmuth and Schulz-Menger; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Aortic Stenosis
- Bicuspid Aortic Valve
- Aortic Valve Stenosis
- Aortic Dilatation
- Valvular Lesion
In a large series of 216 consecutive patients CMR could noninvasively differentiate various types of bicuspid aortic valve (BAV) morphology. BAV type was related to the frequency of stenosis but not to the frequency of aortic dilatation.
Bicuspid aortic valve (BAV) represents the most frequent congenital cardiac abnormality frequently resulting in premature valvular degeneration as well as aortic dilatation. In a large series of consecutive adult patients we describe the distribution of BAV types and the associated valvular and aortic abnormalities.
Among patients undergoing CMR for various clinical reasons between 2004 and 2009, we retrospectively identified 131 patients from our digital archive. Since 2010, we prospectively enrolled 85 consecutive patients with BAV. Using a 1.5 T scanner we obtained SSFP cine movies during breathhold across the aortic root aligned to the aortic valve plane. Slice thickness was 5 mm, in plane resolution typically 1.9 mm/pixel. Valve morphology was described on cine loops according to the surgical Sievers classification based on the presence and the position of a raphe in BAV. Using the cine loops the morphology a planimetry of valve orifice area (AVA) was done. Aortic valve stenosis (AS) was considered, if AVA < 2 cm2. Aortic regurgitation (AR, defined as regurgitation fraction > 10%) was quantified with phase contrast measurements during breathhold across the sinutubular junction. Aortic dilatation (diameter > 40 mm) was evaluated on contiguous axial gradient echo images across the chest and on additional 3D-MRA images, if available. Unclear cases and exclusion of degenerative tricuspid valves were solved by consensus.
Distribution of BAV morphology based on Sievers classification
CMR can noninvasively differentiate various morphologies in BAV. Whereas aortic dilatation was evenly distributed among BAV subtypes in our series, the frequency of aortic stenosis varied among BAV subtypes. Early differentiation of BAV subtype may help to guide patient management.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.