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- Open Access
The diagnostic performance of non-contrast T1-mapping in patients with acute myocarditis on cardiovascular magnetic resonance imaging
© Ferreira et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Cardiovascular Magnetic Resonance
- Diagnostic Performance
- Late Gadolinium Enhancement
- Cardiovascular Magnetic Resonance Imaging
- Acute Myocarditis
Non-contrast T1-mapping using ShMOLLI can serve as a novel CMR diagnostic criterion in patients presenting with suspected acute myocarditis.
The accurate diagnosis of acute myocarditis on cardiovascular magnetic resonance imaging (CMR) often requires multiple modalities, including T2-weighted (T2w), early and late gadolinium imaging. T1-mapping is an emerging technique which is also sensitive to acute changes in free water content. We hypothesized that non-contrast T1-mapping using the novel Shortened Modified Look-Locker Inversion Recovery (ShMOLLI) sequence can serve as a new diagnostic criterion for acute myocarditis.
Non-contrast T1-mapping using ShMOLLI has a high diagnostic performance for acute myocarditis and may be used as a novel additional CMR diagnostic criterion.
This study is funded by the Oxford National Institute for Health Research Biomedical Research Centre Programme. VMF is funded by the Alberta Heritage Foundation for Medical Research (AHFMR) and the University of Oxford Clarendon Fund Scholarship. Dr. Robin Choudhury is a Wellcome Trust Senior Research Fellow in Clinical Science. Stefan Neubauer and Robin Choudhury acknowledge support from the British Heart Foundation Centre of Research Excellence, Oxford.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.