- Poster presentation
- Open Access
Acquisition and visualization of 5D respiratory-resolved cardiac MRI
© Wu et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Diastolic Dysfunction
- Respiratory Cycle
- Free Breathing
- Cardiac Phase
- Respiratory Phase
We image the heart during free breathing and explicitly resolve 3D volumetric information over both the cardiac and respiratory cycles to capture a 5D view of the heart. This 5D dataset can be displayed in a variety of ways to study disease states that exhibit variations in cardiac function with respect to respiration, such as pericardial tamponade/constriction and diastolic dysfunction.
In conventional cardiac MRI, respiratory effects are suspended or counteracted to avoid artifacts. However, in many disease states, such as pericardial tamponade/constriction and diastolic dysfunction, it is precisely variations in cardiac morphology/function with respect to respiratory changes that reflect the pathophysiology and should be studied. In this work, we image the heart during free breathing and explicitly resolve a 3D volume over both cardiac and respiratory cycles. We explore a range of options for visualizing the information captured in this 5D state of the heart.
Free-breathing 5D cardiac MRI is a rapid and robust technique for capturing a respiratory-resolved view of the heart. Respiratory cine and M-mode displays can help to visualize phenomena such as inspiratory septal shift in constrictive disease. Other display options, such as volume-rendered cines, are also possible.
NIBIB T32 EB009035; NHLBI R01 HL039297; AHA 11POST7420014; GE Healthcare.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.