- Poster presentation
- Open Access
Through-time 3D radial GRAPPA for whole heart cardiac imaging
© Seiberlich et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- High Acceleration Factor
- bSSFP Sequence
- Cine Frame
- Undersampled Data
- Single Breathhold
Through-Time 3D Radial GRAPPA can be used to reconstruct 3D CINE images covering the whole heart in a single breathhold.
Through-Time Non-Cartesian GRAPPA has been previously demonstrated for real-time 2D cardiac imaging (Seiberlich, et al. Magn Reson Med. 2011 Feb;65(2):492-505.). This parallel imaging method works by acquiring several fully-sampled non-Cartesian datasets with a low temporal resolution, and using the coil sensitivity information from these datasets to reconstruct highly undersampled non-Cartesian data acquired in real-time. By modifying this through-time non-Cartesian GRAPPA method to reconstruct highly undersampled 3D data, whole heart 3D CINE images can be generated using data acquired in a single breathhold.
A total of 20 fully-sampled 3D stack-of-stars radial datasets were acquired during free-breathing with no EKG gating using a 1.5T Siemens Espree and the following parameters: bSSFP sequence, TE=1.52ms, TR=3.04ms, matrix size = 128x128x20, projections/partition=128, FOV=300x300x90mm3, Flip Angle=45°, 5/8 Partial Fourier, 18 receiver channels. Segmented undersampled data (using only 16 projections/partition, an acceleration factor of R=8) were acquired with EKG gating and the above parameters during a breathhold for 15 heartbeats, resulting in 15 CINE frames. In order to perform the calibration, each of the time frames and partitions were employed as separate sources of calibration information; thus, a total of 300 repetitions could be used to generate the through-time GRAPPA weight sets. After reconstruction, the undersampled data yielded fully-sampled 3D CINE images, each with a temporal footprint of 48ms, an in-plane resolution of 2.3mm2, and a through-plane resolution of 6mm. The total acquisition time was 116s for the calibration and approximately 15 s for the breathhold CINE acquisition.
By combining through-k-space calibration used in standard parallel imaging with through-time calibration, undersampled 3D radial CINE datasets can be reconstructed to yield CINE images at similar temporal resolutions as 2D CINE images with coverage of the entire heart in a single breathhold.
The authors would like to acknowledge funding from Siemens Medical Solutions and NIH grants 1RO1HL094557 and 5K99EB011527.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.