- Poster presentation
- Open Access
Moderate dietary weight loss reduces myocardial triglycerides in obese women
© Utz et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Obese Woman
- Lifestyle Intervention
- Filling Rate
- Peak Filling Rate
- Hypocaloric Diet
Excessive myocardial triglyceride (MTG) content in obesity and type 2 diabetes is associated with impaired cardiac function. Previous studies suggest that MTG could be mobilized through lifestyle interventions. We assessed influences of moderate dietary weight loss in non diabetic obese women on MTG content and cardiac function.
Non diabetic overweight and obese women were submitted to a six months hypocaloric diet with either fat or carbohydrate restriction. Cardiac structure and function was assessed by magnetic resonance imaging (MRI) and MTG content by proton spectroscopy (MRS) in 35 subjects at baseline and follow-up. Anthropometric and metabolic parameters as well as cardio-respiratory fitness were measured.
Moderate dietary weight loss significantly reduced MTG content in women with uncomplicated obesity. Macronutrient composition of the diet did not significantly affect the extent of MTG reduction.
This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.