Wall shear stress vectors derived from 3D PC-MRI at increasing resolutions in an intracranial aneurysm phantom
© van Ooij et al; licensee BioMed Central Ltd. 2012
Published: 1 February 2012
Wall shear stress (WSS) is the friction force that blood flow exerts on the vessel wall. It is thought to affect the function of endothelial cells and the development of atherosclerosis and aneurysms. A promising technique to measure blood flow is three-dimensional phase contrast MRI (3D PC-MRI). Due to limited spatial resolution and SNR, estimating WSS from time-resolved 3D PC-MRI is challenging. In this study, a recently in-house developed WSS algorithm is tested on 3D PC-MRI in an intracranial aneurysm phantom, measured with steady flow at different resolutions.
For accurate WSS estimations, resolution and SNR must be as high as possible. This is difficult to attain in clinical 4D PC-MRI protocols. To obtain a qualitative indication of WSS distributions, acquisitions at low resolution may be sufficient.
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