- Workshop presentation
- Open Access
Hemodynamic characterization of Aortic Valve Bypass Surgery (AVBS) using patient-specific computational models based on MRA and PCMR
© Lam et al; licensee BioMed Central Ltd. 2012
- Published: 1 February 2012
- Computational Fluid Dynamics
- Magnetic Resonance Angiography
- Thoracic Aorta
- Computational Fluid Dynamics Model
- Aortic Valve Stenosis
20 patients received a follow-up MRI scan 6-12 months after surgery. Contrast-enhanced MRA was used for patient-specific 3D geometry reconstruction. PCMR images were acquired at multiple locations along the descending thoracic aorta and the conduit (Fig 1). Average velocities were obtained from segmented vessels at the native aortic valve and the descending thoracic aorta on PCMR images and used for inlet boundary conditions. Patients with retrograde flow in the descending thoracic aorta (flow from conduit to arch vessels) were selected for modeling. All CFD models were simulated with Fluent ANSYS, Inc. and post-processed using Tecplot.
CFD based on MRA and PCMR can be used to model hemodynamics in AVBS patients. Simulation results indicate that arch vessel perfusion is composed of both native aorta and conduit flow and depends highly on the native aortic flow. CFD results show regions of highly disturbed flow at the inner aortic arch, indicating a possible mechanism for post-surgical complications.
This project was funded by the NIH T32 Training Grant.
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