- Poster presentation
- Open Access
Diffusion tensor imaging of formalin fixed infarcted porcine hearts
© Mazumder et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Fractional Anisotropy
- Diffusion Tensor Imaging
- Fiber Length
- Random Motion
- Fiber Tract
Diffusion is the random motion exhibited by molecules as a result of thermal agitation. In biological tissues the random motion of water molecules is anisotropic since they are restricted by the tissue structure. The application of diffusion tensor imaging (DTI) makes it possible to quantify the amount of diffusion in tissues. Further processing allows a 3D visualization of the fiber architecture by tracking the fiber trajectories within a tissue. Experimental evidence has shown that fiber architecture in the myocardium changes with the onset of myocardial infarction . Furthermore, the myocardium undergoes remodeling as the infarction progresses over time. The aim of this study is to evaluate the remodeling of the fiber architecture in an infarcted porcine heart.
The results demonstrated remodeling of fiber tissue structure in the LVM as a result of infarction.
However, more studies are warranted to confirm our analogy and establish the technique.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.