Interleaved T2 preparation for simultaneous coronary artery and pulmonary artery and vein visualization
© Butzbach et al; licensee BioMed Central Ltd. 2013
Published: 30 January 2013
Patients with congenital heart disease (CHD) were examined with a dynamic T2prep 3D-whole heart acquisition (mean age 3 +/- 6.4 years, n=4) and compared to ten healthy subjects (mean 34 years, STD +/- 6.87, n=10) in diastole. An independent samples t-test and a paired t-test were performed to compare normally distributed variables.
An increase of SNR was seen in children and healthy volunteers in the subtracted images. After analyzing the B0-map, statistically significant differences were shown for the pulmonary veins (p<0.027).
The brightest signal in all cases was observed in the pulmonary circulation. This effect is caused by an off-resonance phenomenon. Whilst using T2-preparations pulses, the B0-field inhomogeneity acts as a susceptibility background gradient and leads to a suppression of moving tissue and blood and consequently to a signal enhanced pulmonary circulation in subtraction images.
Division of Imaging Sciences, The Rayne's Insitute
King's College London
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