- Poster presentation
- Open Access
Cardiac MRI correlates of diastolic left ventricular function assessment by echocardiography
© Saba et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Diastolic Function
- Mitral Annulus
- Left Ventricular Systolic Function
- Atrial Contraction
- Mitral Inflow
Transthoracic echocardiography (TTE) provides non-invasive measures of diastolic left ventricular (LV) function by assessing mitral inflow and mitral annular motion. Given the excellent spatial and temporal resolution of CMR, we developed a novel method to calculate several correlative measures of diastolic and systolic LV function. The maximum velocity of the atrioventricular junction (AVJ) during early diastole represents a correlate of the maximum velocity of the mitral annulus (e'). To determine the correlation between CMR and TTE indices of diastolic function, we performed a retrospective analysis.
The mean and standard deviation EF determined by CMR was found to be 38% ± 15%. Significant correlations were found between EF and MD (r = 0.604, p < 0.001), both measures of longitudinal LV systolic function, as well as MVED and e' (r = 0.362, p = 0.030), which reflect peak mitral annular velocities during early, passive diastolic filling. A negative correlation was observed between MVED and E/e' (r = -0.425, p = 0.010), suggesting an inverse relationship between peak AVJ velocity during early diastole and left atrial pressure. Significant correlations were also noted for VDS and e' (r = 0.473, p = 0.004), VDS and a' (r = 0.382, p = 0.045), as well as VDS/MVED and DT (r = 0.350, p = 0.034).
Maximum displacement of the AVJ determined by CMR correlates with EF and serves as a simple measure of LV systolic function. MVED provides a novel CMR correlate of the tissue Doppler echocardiography measure e'. Assessment of AVJ motion variables may provide additional CMR metrics of systolic and diastolic function without increasing scanning time.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.