- Oral presentation
- Open Access
Eliminating dark-rim artifacts in first-pass myocardial perfusion imaging
© Sharif et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Myocardial Perfusion Imaging
- Gibbs Effect
- Award 11POST7390063
- Cartesian Image
- Gibbs Ringing
Healthy human volunteers (N=12) were imaged on a 3T scanner (Siemens Verio). Two FPP scans (SR-prepared FLASH) were performed at rest (>10 minutes gap) using a single-shot radial pulse sequence followed by a single-shot Cartesian sequence (common parameters: FOV read =270-350 mm; BW ≈800 Hz/pixel; flip angle = 12°; TR =2.4-2.6 ms; TI =100 ms). Both scans were accelerated using rate 2 parallel imaging (TGRAPPA for Cartesian and SENSE for radial) and the number of readouts per frame was matched within 10% (range: 48-56). Scans were visually read for artifact by 2 expert readers blinded to the study protocol using a consensus 0-4 scoring scheme (0:no DRA; 4:severe DRA).
In this work, we demonstrated that radial imaging is capable of significantly reducing the dark rim artifact even in the early myocardial enhancement phase of a first-pass perfusion image series, due to its inherent robustness to Gibbs ringing. Such artifacts may confound interpretation and diagnosis of subendocardial perfusion defects (which may "fill in" early during the myocardial enhancement phase). Advanced (e.g., model-based/iterative) reconstruction techniques with radial acquisition can be used to improve image quality while preserving the described dark-rim-minimizing properties.
Grant sponsors: American Heart Association Postdoctoral Fellowship Award 11POST7390063; National Institutes of Health grants nos. NHLBI HL38698, HL091989, N01-HV-68161, N01-HV-68162, N01-HV-68163, N01-HV-68164, U01 HL649141, and NIH CTSI UL1TR000124.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.