- Oral presentation
- Open Access
A new variant of apical hypertrophic cardiomyopathy? T wave inversion and relative but not absolute apical left ventricular hypertrophy
© Flett et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Hypertrophic Cardiomyopathy
- Wave Inversion
- Fund Council
- High Education Fund
- Apical Aneurysm
We retrospectively reviewed 2662 CMR scans (Siemens 1.5 T) performed over a 20 month period. Seventy-five patients were identified in whom there was TWI in the anterior leads and a suspicion of HCM. These, along with 60 healthy volunteers and 50 hypertensives, were analyzed for imaging features consistent with cardiomyopathy: relative apical hypertrophy (Apical:Basal WT Ratio: ABR>1), left atrial dilatation, >2cm apical cavity obliteration, scar and apical aneurysm.
A cohort of individuals exists with T wave inversion, relative apical hypertrophy and additional imaging features of HCM that are not captured by existing criteria. We believe these represent an apical HCM variant.
J.C.M is supported by the Higher Education Funding Council for England.
This work was undertaken at the University College London Hospital and University College London, which receive a proportion of funding from the Department of Health's National Institute for Health Research Biomedical Research Centres funding scheme.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.