- Oral presentation
- Open Access
Improving the accuracy of multi breath-hold diffusion tensor MRI tractography of the heart using dynamic motioncorrection
© Mekkaoui et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Motion Correction
- Fiber Track
- Rigid Registration
- Physiological Noise
- Motion Correction Method
Diffusion Tensor MRI (DTI) tractography of the human heart can be performed in vivo, but requires multiple breatholds per slice to achieve adequate SNR [1, 2]. The physiological noise inherent to multiple breatholds results in a diffusion-encoded volume in which the data vary as a function of space and time. This may hinder the assessment of diffusion based-indices in the heart and accurate tractography of myofiber architecture. In this study, we investigate the effect of a novel automated motion correction method on in vivo DTI of the heart.
DTI tractography can be performed in vivo over multiple breatholds, but is affected by physiological noise. Here, we show that motion correction over space and time can reduce the noise produced by multiple breatholds while increasing the quality of the resulting tractograms. This approach paves the way for the use of free breathing navigator-based DTI for high-resolution tractography of the heart.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.