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  • Oral presentation
  • Open Access

European Cardiovascular Magnetic Resonance (EuroCMR) registry - multi national tesults from 57 centers in 15 countries

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Journal of Cardiovascular Magnetic Resonance201315 (Suppl 1) :O96

https://doi.org/10.1186/1532-429X-15-S1-O96

  • Published:

Keywords

  • Cardiomyopathy
  • Cardiovascular Magnetic Resonance
  • Interim Analysis
  • Hypertrophic Cardiomyopathy
  • Suspected Coronary Artery Disease

Background

The EuroCMR registry determined indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting.

Furthermore, interim analyses of two specific protocols evaluating the prognostic potential of CMR in patients with coronary artery disease (CAD) and hypertrophic cardiomyopathy (HCM) are presented.

Methods

Multi-center registry with consecutive enrollment of patients in 57 centers in 15 countries [1].

Results

27,781 patients were enrolled. The most frequent indications were risk stratification in CAD/ischemia (34.2%), workup of cardiomyopathies (32.2%) and assessment of viability (14.6%). Image quality was diagnostic in 98%. Severe complications were rare (0.03%).

In 61.8% CMR findings had an impact on patient management. In 8.7% the final diagnosis changed based on CMR findings (Table 1).
Table 1

Impact of CMR on patient management by indication

 

Myocarditis/ Cardiomyopathy

Suspected CAD/Ischemia

Viability

All (from n = 27781)

32.2%

34.2%

14.6%

New diagnosis

11.4%

8.1%

5.3%

Therapeutic consequences:

   

Change in medication

25.3%

24.3%

33.2%

Invasive procedure

6.9%

23.1%

24.2%

Hospital discharge

10.4%

14.3%

6.9%

Impact on patient management (new diagnosis and/or therapeutic consequence)

55.1%

71.4%

71.5%

Kaplan-Meier survival curves of the interim analyses showed low adverse event rates in patients with suspected CAD with a normal stress CMR (1.0% per year), and in HCM without delayed enhancement (2.7% per year).

Conclusions

The most important CMR indications in Europe are risk stratification in suspected CAD/ischemia, work-up of cardiomyopathies and assessment of viability. CMR is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have a strong impact on patient management. Interim analyses underscore the prognostic value of clinical routine CMR in patients with CAD and HCM.

Funding

Medtronic Inc., Minneapolis MN, USA.

Novartis International AG, Basel, Switzerland.

Siemens Health Care, Erlangen, Germany.

Authors’ Affiliations

(1)
Cardiology, Comprehensive Cardiology, Stamford, CT, USA
(2)
Cardiology, Contilia Heart and Vascular Center, Essen, Germany
(3)
Cardiology, C.N.R./Regione Toscana "G. Monasterio Foundation", Pisa, Italy
(4)
Cardiology, Cardiac MR Centre, University Hospital (CHUV) Lausanne, Lausanne, Switzerland
(5)
Cardiology, VU Medical Centre, Amsterdam, Netherlands
(6)
Cardiology, Hospital Agatharied, Hausham, Germany
(7)
Cardiology, Klinikum Ludwigsburg, Ludwigsburg, Germany
(8)
Barts and The London NIHR Biomedical Research Unit, The London Chest Hospital, London, UK
(9)
Division of Imaging Sciences, King's College London BHF, London, UK
(10)
CMR Unit, Royal Brompton Hospital, London, UK
(11)
Internal Medicine, Krankenhaus Benrath, Düsseldorf, Germany
(12)
Cardiology, Donauklinikum Tulln, Tulln, Austria
(13)
Department of Statistics, Institut für Herzinfarktforschung, Ludwigshafen, Germany
(14)
Cardiology, Robert Bosch Medical Center, Stuttgart, Germany

References

  1. Wagner A: . J Cardiovasc Magn Resn. 2009Google Scholar

Copyright

© Wagner et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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