- Oral presentation
- Open Access
Clinical validation of free breathing Respiratory Triggered Retrospectively Cardiac Gated Cine Steady-State Free Precession (RT-SSFP) imaging in sedated children
© Krishnamurthy et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Image Quality Assessment
- Free Breathing
- Blinded User
- Respiratory Trigger
- Sedate Child
Cine steady-state free precession (SSFP) is the preferred sequence for ventricular function evaluation. However, SSFP demands uninterrupted RF excitation to maintain steady-state (SS) during suspended respiration. This is feasible in adults who can perform breath-holding (BH), but is difficult to accomplish in sedated or uncooperative children. To overcome this, many pediatric groups routinely perform multi-NSA acquisitions (MN) during free breathing. In this work, we validate a respiratory triggered (RT) SSFP sequence that drives the magnetization to steady-state before commencing cardiac gated cine acquisition in sedated pediatric population.
This prospective study was performed on 12 sedated children with congenital heart disease (age: 7±3 yrs) with IRB approval.
All imaging was performed on a commercial MR scanner (1.5 T, Achieva, Philips Healthcare). Identical imaging parameters were used for MN and RT cine SSFP sequences  covering both the ventricles in short-axis (SA) orientation (TR/TE/flip angle: 3/1.5/60; acquired voxel size: 1.5-1.9 x 1.5-2.1 x 7-8 mm3; SENSE acceleration factor: 2; temporal resolution: 30-45 ms; acquisition time: 8-10 RR intervals/slice).
Table 1RT vs. MN (n = 12)
Limit of Agreement
The free breathing RT-SSFP sequence allows clinically diagnostic images in sedated children without any penalty for total scan time, and offers improved myocardial blood-pool contrast, and edge definition when compared to MN-SSFP.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.