- Poster presentation
- Open Access
Reliability of left ventricular noncompaction imaging criteria - the fractal facts
© Captur et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Fractal Dimension
- Fractal Method
- Repeatability Coefficient
- High Education Fund
- Ventricular Noncompaction
Left ventricular noncompaction (LVNC) is a cardiomyopathy with important prognostic implications. Identification of patients with LVNC using current criteria is challenging. Fractal analysis is a novel approach which summarises global LV trabecular complexity as a continuous variable, the fractal dimension, enabling the establishment of ethnically and disease-appropriate reference ranges for trabeculation.
Fractal analysis of LV trabeculae demonstrates good reproducibility and is more accurate in diagnosing LVNC than other techniques. The fractal dimension, if used in clinical trials would more than halve the number of patients required to detect clinically relevant differences in trabecular complexity.
J.C.M is supported by the Higher Education Funding Council for England.
G.C. is supported by the University College London through a Graduate Research Scholarship and by the European Union through a Science and Technology Research Grant.
This work was undertaken at the University College London Hospital and University College London, which receive a proportion of funding from the Department of Health's National Institute for Health Research Biomedical Research Centres funding scheme.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.