- Poster presentation
- Open Access
Myocardial iron quantification using T2-prepared SSFP parametric images at 3 Tesla
© Camargo et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Iron Overload
- Chelate Therapy
- Diagnostic Image Quality
- Iron Chelate Therapy
Quantification of myocardial iron overload is critical for the management of patients with hemochromatosis. The effects of excess iron over T2 and T2* relaxation times are well known and both measures strongly correlate with iron concentration. Due to its lower sensitivity to B0 inhomogeneities, T2 has theoretical advantages over T2*, but the latter became the clinical standard as it can be easily obtained in a fast one breath-hold ECG gated multi-echo GRE sequence. T2* is especially challenging at 3T due to greater B0 inhomogeneities at higher field strengths. We aimed to validate a recently developed T2-prepared SSFP sequence that quantifies myocardial T2 times at 3T, compared to standard GRE based multi-echo T2* times at 1.5T.
Our results show that myocardial T2 values obtained with a T2-prepared SSFP parametric sequence can potentially serve as a valuable tool for quantification of iron overload at 3T.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.