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- Open Access
The diagnostic performance of novel techniques for the detection of acute myocarditis: a clinical study using cardiovascular magnetic resonance imaging
© Ferreira et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Late Gadolinium Enhancement
- Signal Intensity Ratio
- Cardiovascular Magnetic Resonance Imaging
- Acute Myocarditis
The accurate diagnosis of acute myocarditis on cardiovascular magnetic resonance imaging (CMR) often requires multiple modalities, including T2-weighted (T2W), early and late gadolinium imaging. Novel CMR techniques are now available, including bright-blood T2W-CMR, and T1-mapping which is also sensitive to changes in free water content. We hypothesized that these emerging methods can serve as new diagnostic criteria for myocarditis.
T1-mapping showed superior diagnostic performance compared to conventional dark-blood and newer bright-blood T2W-CMR in the detection of acute myocarditis. T1-mapping and bright-blood T2W-CMR may be used as novel diagnostic criteria for the assessment of acute myocarditis.
This study is funded by the Oxford National Institute for Health Research Biomedical Research Centre Programme. VMF is funded by the Alberta Innovates Health Solutions (AIHS) Clinical Fellowship and the University of Oxford Clarendon Fund Scholarship. Dr. Robin Choudhury is a Wellcome Trust Senior Research Fellow in Clinical Science. Stefan Neubauer and Robin Choudhury acknowledge support from the British Heart Foundation Centre of Research Excellence, Oxford
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.