Feasibility of three-dimensional (3D) balanced steady-state-free-precession (bSSFP) myocardial perfusion MRI at 3 Tesla using local RF Shimming with dual-source RF transmission
© Jogiya et al; licensee BioMed Central Ltd. 2013
Published: 30 January 2013
Three-dimensional myocardial perfusion MRI offers better myocardial coverage than conventionally used two-dimensional methods. bSSFP three-dimensional myocardial perfusion MRI at 3 Tesla potentially offers further improvement of signal characteristics and may enhance the use of three-dimensional myocardial perfusion MRI for clinical application.
Twenty-five healthy volunteers and 2 patients were included upon written informed consent and local ethics committee approval. Dynamic contrast-enhanced 3D bSSFP perfusion imaging was performed on a 3 Tesla MRI scanner equipped with dual-source RF transmission technology (MultiTransmit; Philips Healthcare, The Netherlands).
Compared with an equivalent 3D spoiled gradient echo method (TFE), mean SNR was (30.4 vs 24.4, respectively, P=0.24), but signal homogeneity measured in the myocardium was improved (14.98% vs 11.15%, respectively, p=0.015).
Three-dimensional bSSFP myocardial perfusion MRI using local RF Shimming with dual-source RF transmission at 3 Tesla is feasible with improved signal characteristics. Image artifacts however remain an important limitation.
Prof. Plein is funded by British Heart Foundation fellowship FS/10/62/28409 and receives research grant support from Philips Healthcare.
Prof. Kozerke receives funding from the Swiss National Science Foundation (grant number CR3213_132671/1) and research support form Bayer (Switzerland) AG. Prof. Nagel receives grant support from Bayer Healthcare and Philips Healthcare.
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