- Poster presentation
- Open Access
Type of aortic valve replacement influences ascending aortic flow characteristics - a pilot study using 4D flow MRI
© von Knobelsdorff-Brenkenhoff et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Wall Shear Stress
- Aortic Valve Replacement
- Aortic Wall
- Mechanical Prosthesis
- Native Aortic Valve
Prosthesis-related alterations of blood flow in the ascending aorta after aortic valve replacement (AVR) may influence aortic remodeling. The study aimed at analyzing ascending aortic flow characteristics after various types of AVR.
Flow-sensitive four-dimensional magnetic resonance imaging (4D-flow) was acquired in 38 AVR patients (n=9 mechanical, n=8 stentless bioprosthesis, n=14 stented bioprosthesis, n=7 autograft) and 9 healthy controls. Analysis included grading of vortex and helix flow (0-3 point scale), assessment of systolic flow eccentricity (1-3 point scale), and quantification of the segmental distribution of peak systolic wall shear stress (WSSpeak) in the ascending aorta.
The flow characteristics in the ascending aorta in all AVR types were different from volunteers with native aortic valve, and they differed between the various types of AVR.
FvKB is supported by the Else Kröner-Fresenius Stiftung (Bad Homburg, Germany). AJB is funded by the Whitaker Postdoctoral and Fulbright Grants (New York, USA). MM is supported by the NMH Excellence in Academic Medicine (EAM) Program 'Advanced Cardiovascular MRI Research Center' (Chicago, USA).