- Poster presentation
- Open Access
3D respiratory resolved phase contrast imaging of the aorta
© Schrauben et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Flow Waveform
- Respiratory Phasis
- Blood Flow Analysis
- Prospective Gating
- Temporal View
Respiratory motion compensation is essential for reproducible and robust cardiovascular MRI. Traditionally, breathholds or prospective gating by bellows or navigator signals limit data acquisition to the quiescent phase of respiration . These approaches do not capture any variations of blood flow over the respiratory cycle, yet respiration has been shown to significantly affect flow in the great vessels . The purpose of this pilot study was to adapt a 3D radially undersampled PC MR sequence (PC VIPR [3, 4]) for use with our retrospective dual-gated (cardiac and respiratory) reconstruction to evaluate respiratory effects on net flow and cardiac flow waveforms.
A 3D radial double-gated acquisition and reconstruction that allows for blood flow analysis over the cardiac cycle is presented. Data acquired in healthy volunteers shows significant increased blood flow during expiration compared to inspiration in the Ao. The same effect is marginal in the DAo. Acquisition throughout the respiratory cycle does not prolong scan time while allowing for retrospective selection of arbitrary measurement planes. Further studies are warranted to quantify these respiratory effects in other vessels and to investigate implications for assessing flow.
NMSS fund RC1003-A-1, NIH grant 2R01HL072260, and GE Healthcare
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.