- Poster presentation
- Open Access
Segment-based myocardial T1 and T2 mapping at 3T: feasibility and normal values
© von Knobelsdorff-Brenkenhoff et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Single Shot
- Steady State Free Precession
- Myocardial Segment
- Susceptibility Artifact
Myocardial T1 and T2 mapping using cardiovascular magnetic resonance imaging (CMR) is promising to improve disease detection and monitoring. We applied T1 and T2 mapping at 3T to study the technical feasibility and provide reference values in healthy volunteers.
Sixty healthy volunteers (30 males / 30 females, 20 in each age group: 20-39 years, 40-59 years, 60-80 years) underwent T1 and T2 mapping of the left ventricle in 3 short axis slices. For T2 maps, 3 single shot steady state free precession (SSFP) images with different T2 preparation times (0, 24, 55ms) were acquired (TE 1.0 ms, TR 2.4 ms, voxel 1.9 x 1.9x6 mm3). For T1 maps, Modified Look-Locker Inversion Recovery (MOLLI) technique with 11 single shot SSFP images was used before and after injection of gadolinium contrast (pre-contrast: TE 1.0 ms, TR 2.6 ms, voxel size 1.4-1.7 x 1.4-1.7 x 6 mm3). T1 and T2 relaxation times were quantified for each slice and each myocardial segment.
T2 and T1 mapping at 3T was technically feasible, reference values for each myocardial segment are now provided, and observer dependency was low. However, 3T-related susceptibility artifacts and the relatively wide tolerance interval of T2 and T1 times must be considered during interpretation.
This project is supported by the Else Kröner-Fresenius Stiftung (Bad Homburg, Germany).
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.