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Left ventricular inflow propagation velocity for diastolic function testing: head-to-head comparison between velocity-encoded MRI and color M-mode Doppler echocardiography
© van den Boogaard et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Mitral Valve
- Diastolic Dysfunction
- Diastolic Function
- Ischemic Cardiomyopathy
- Inflow Velocity
The inflow propagation velocity (Vprop) of the early filling wave has been proposed as an accurate marker of left ventricular (LV) diastolic function . Traditionally, Color M-mode echo Doppler is used for Vprop-assessment. However, this method has not been validated against an alternative modality such as velocity-encoded (VE) MRI for assessing Vprop. The purpose of this study was to compare Vprop assessed from high temporal VE MRI with Color M-mode echo Doppler in patients with ischemic cardiomyopathy.
Diastolic dysfunction classification using Vprop<45cm/s as cut-off criterion.
Assessment of Vprop from VE MRI showed good correlation with echo Doppler with Pearson R = 0.71 (p<0.001). A small statistically non-significant overestimation was present on VE MRI compared to echo Doppler of 3±24cm/s (p=0.40). Vprop was not statistically significant correlated with Epeak velocity (Pearsons R=0.14, p=0.41), both assessed with VE MRI.
VE MRI and echo Doppler showed good agreement (kappa 0.72), with sensitivity/specificity of 84%/82% for diastolic function classification by Vprop.
VE MRI and Color M-mode echo Doppler showed good correlation and agreement for Vprop-assessment in ischemic cardiomyopathy regardless of LV inflow velocity, with a high sensitivity and specificity for VE MRI classifying diastolic dysfunction.
STW project 11626
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