- Poster presentation
- Open Access
Combining extracellular volume fraction imaging and T2 quantification by cardiovascular magnetic resonance in patients with clinically suspected myocarditis
© Radunski et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Late Gadolinium Enhancement
- Fraction Imaging
- Extracellular Volume Fraction
Assessing the extracellular volume fraction (ECV) by T1 mapping and T2 quantification are promising quantitative cardiovascular magnetic resonance (CMR) tools in acute myocardial injury. This study evaluated the diagnostic value of combining ECV imaging and T2 quantification in patients with clinically suspected myocarditis.
There was a moderate correlation between global ECV and global T2 values (r=0.51, p<0.01). Current clinical and CMR criteria identified 31 (86 %) patients with myocarditis and 5 (14 %) patients without myocarditis in this study population. Global ECV was significantly larger in patients with myocarditis (35 (32-39) %) compared to patients without myocarditis (26 (24-37) %; p<0.05). A non-significant difference in global T2 was found between patients with (61 (58-66) ms) and without myocarditis (55 (52-62) ms; p=0.08). Presence of a global ECV ≧ 32 % and/or a global T2 ≧ 58 ms provided positive and negative predictive values to identify patients with myocarditis of 94 and 60 %, respectively (p<0.05).
Our findings indicate a potential incremental diagnostic value of combining ECV imaging and T2 quantification in patients with clinically suspected myocarditis.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.