- Workshop presentation
- Open Access
High spatial and temporal myocardial CINE T2* mapping at 7.0 T: a feasibility study
© Hezel et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Cardiovascular Magnetic Resonance
- Myocardial Segment
- Cardiovascular Magnetic Resonance Imaging
- High Magnetic Field Strength
- Myocardial Tissue Characterization
Myocardial tissue characterization using T2* relaxation mapping techniques is an emerging application of clinical cardiovascular magnetic resonance imaging. The increase in microscopic susceptibility at higher magnetic field strengths renders myocardial T2* mapping at ultrahigh magnetic fields conceptually appealing. This work demonstrates the feasibility of myocardial T2* imaging at 7.0 T and examines the applicability of temporally-resolved and high spatial resolution myocardial T2* mapping.
Imaging was conducted using a 7.0 T whole body MR scanner (Magnetom, Siemens Healthcare Erlangen) together with a 16 channel TX/RX coil array on 8 healthy subjects without any known history of cardiac disease. 9 CINE datasets were acquired with echo times ranging from 2.04ms to 10.20ms with a interleaved multi-shot multi-echo gradient echo technique over three breath holds. Other imaging parameters were set to: flip angle=20°, acquisition data matrix=256x224, FOV=(288x252)mm2, in-plane resolution=(1.1x1.1)mm2, slice thickness=4mm and acceleration using GRAPPA (R=3). Prior to T2* mapping, volume selective B0 shimming was conducted to reduce static magnetic field inhomogeneities.
Our results underscore the challenges of myocardial T2* mapping at 7.0 T due to the propensity to macroscopic susceptibility artefacts and T2* shortening, but demonstrate that these issues can be offset by using tailored shimming techniques together with dedicated acquisition schemes.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.