- Workshop presentation
- Open Access
Diffusion tensor imaging of formalin fixed infarcted porcine hearts: a comparison between 3T and 1.5T
© Mazumder et al; licensee BioMed Central Ltd. 2013
- Published: 30 January 2013
- Fractional Anisotropy
- Diffusion Tensor Image
- Fiber Length
- Siemens Healthcare
- Fiber Tract
Diffusion Tensor Imaging (DTI) quantifies the amount of anisotropic diffusion exhibited by biological tissues. Processing DTI images allow a 3D visualization of the fiber architecture by tracking the fiber trajectories within the tissue. Experimental evidence has shown that the myocardium undergoes remodeling as myocardial infarction progresses over time. The aim of this study is to investigate and compare the fiber architecture in an infarcted porcine heart using DTI at 1.5T and 3T, to analyze the effect of high field magnets in imaging.
From this preliminary study we observe that the fibers from both the scanners are consistent in terms of the lengths being short and disarrayed around the infracted region compared to the rest of the LVM. We also observe that in the data from the 1.5T scanner fibers tracked are smoother and more in number compared to the data from the 3T scanner. However, more studies are warranted to confirm our analogy and establish the technique.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.