- Oral presentation
- Open Access
Artifact reduction with a wideband late gadolinium enhancement (LGE) MRI technique for patients with implanted cardiac devices: a two-center study
© Rashid et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Late Gadolinium Enhancement
- Implantable Cardioverter Defibrillator
- Myocardial Scar
- Late Gadolinium Enhancement Image
- Cardiac Device
The HI artifacts in LGE images of ICD patients are caused by severe off-resonance produced by the ICD. Spins in the affected myocardium are not inverted by the IR pulse and give rise to the HI artifacts. In the new sequence, a wideband (3.8 kHz) IR pulse was implemented to replace the standard pulse with 1.1 kHz spectral bandwidth, thereby eliminating the HI artifacts [3, 4]. The wideband LGE was implemented at the medical centers of the University of California, Los Angeles (UCLA), and the University of Pennsylvania (Penn). A total of 25 patients with ICDs and PMs (UCLA: 19, Penn: 6), were imaged using the conventional and the wideband LGE technique. In each image set, the left ventricle was divided into 13 segments (basal, mid-ventricular, and apical, each having posterior, lateral, anterior and septal segments, and an individual apex segment). Artifact-containing segments in each patient were identified by two attending radiologists.
We have developed a wideband LGE technique to eliminate the HI artifacts seen in LGE MRI of patients with ICDs. This technique was implemented at two centers and successfully evaluated on 25 patients, leading to prominent reduction of the HI artifacts. The wideband LGE technique may enable widespread utility of LGE MRI in patients with implanted cardiac devices, in whom LGE MRI otherwise could not be used for diagnosis.
NIH 1R21 HL118533
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