- Oral presentation
- Open Access
Native T1-mapping displays the extent and non-ischemic patterns of injury in acute myocarditis without the need for contrast agents
© Ferreira et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Contrast Agent
- Late Gadolinium Enhancement
- Additional Area
- Signal Intensity Ratio
Acute myocarditis is typically diagnosed on CMR using multiple techniques, including late gadolinium enhancement (LGE) imaging, which require contrast administration. T1-mapping is significantly more sensitive than conventional T2-weighted (T2W) and LGE imaging in detecting myocarditis, without the need for contrast agents.
In acute myocarditis, native T1-mapping can display the typical non-ischemic patterns similar to LGE imaging without the need for contrast agents. T1-mapping also detects additional areas of involvement and identifies extra cases beyond T2W and LGE imaging.
This study is funded by the Oxford National Institute for Health Research Biomedical Research Centre Programme. VMF received funding from the Alberta Innovates Health Solutions (AIHS) Clinical Fellowship and the University of Oxford Clarendon Fund Scholarship. RC is a Wellcome Trust Senior Research Fellow in Clinical Science. SN and RC acknowledge support from the British Heart Foundation Centre of Research Excellence, Oxford.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.