- Oral presentation
- Open Access
Native T1 values in discrimination between in acute and chronic myocarditis
© Baydes et al.; licensee BioMed Central Ltd. 2014
- Published: 16 January 2014
- Cardiovascular Magnetic Resonance
- Chronic Stage
- Myocardial Oedema
- Acute Myocarditis
T1 mapping by cardiovascular magnetic resonance (CMR) provides tissue-dependent relaxation times in line with the underlying myocardial composition. In this study, we examined the value of native T1 in differentiation between acute viral myocarditis and chronic stages of healing.
Fifty-three patients with a clinical diagnosis of acute viral myocarditis were compared to fifty-six subjects in clinical convalescence. All subjects underwent assessment of myocardial oedema, function and scar by CMR at 1.5 and 3-Tesla. T1 values were measured in midventricular short-axis slice prior to and after administration of 0.2 mmol/kg of gadobutrol.
We demonstrate that native T1 values can reliably discriminate between patients with acute myocarditis and those subjects in stages of chronic healing at both field strengths. Native T1 values provide a dynamic index of disease activity and progression from acute disease towards clinical resolution.
We would like to acknowledge Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital National Health Service Foundation Trust. Dr. Rocio Hinojar was supported by the Spanish Society of Cardiology.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.